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6% of patients in the Actonel 5 mg daily group and 6. 2% in the Actonel 5 mg daily group and 6. Actonel should be taken according to the dosing instructions to minimize the risk of these events. Compared to the Actonel 5 mg daily group, Actonel 75 mg two consecutive days per month resulted in a slightly higher incidence of hypocalcemia at the end of the first month of treatment (4. In patients with active upper gastrointestinal disease at baseline, the incidence of upper gastrointestinal adverse events was similar between the placebo and Actonel 5 mg daily groups.
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